Empty cleanroom interior with HEPA ceiling, support columns and seamless flooring ready for equipment installation Empty cleanroom interior with HEPA ceiling, support columns and seamless flooring ready for equipment installation

Welcome to our Knowledge Hub!

This hub is a practical guide for anyone new to cleanrooms. Whether you are deciding if you need one, choosing a classification, or planning the design, build and ongoing validation, you’ll find plain-English explanations from the engineers at Angstrom Technology, who design, build, validate and maintain cleanrooms across the UK and Europe.

What our experts say

Read expert perspectives from Angstrom's cleanroom specialists on design, compliance, energy and more.

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FFUs vs Centralised HVAC for Cleanrooms

Should your cleanroom use Fan Filter Units (FFUs) or a centralised HVAC system? Compare the pros, cons, costs, flexibility, and ideal applications of each cleanroom…
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Who is responsible for Cleanroom Compliance?

A regulated Cleanroom only stays compliant if everyone knows their role. In practice, responsibility is shared across the organisation and stakeholders.  
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What do I need to consider when designing a cleanroom?

A Cleanroom project touches far more than just air filters and coverall suits. Missing one key consideration early can lead to expensive changes later.
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How much does a cleanroom cost?

Cleanrooms can vary massively in cost depending on a variety of cost drivers. Typically, the biggest influence is the HVAC system, which must deliver dramatically…
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The running cost of a cleanroom & energy conservation

Cleanrooms are notorious for being massively energy consumptive – often using far more power than a standard manufacturing facility of the same size.
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How do I know what ISO class my cleanroom should be?

A practical framework for choosing the right ISO 14644 cleanroom class, balancing product risk, cost, and customer requirements.
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Do I need a Cleanroom?

What is ISO 14644?

If you’re involved in any validated Cleanroom project, the term “ISO 14644” will most likely appear constantly in the documentation. But what exactly is it,…
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