Empty cleanroom interior with HEPA ceiling, support columns and seamless flooring ready for equipment installation Empty cleanroom interior with HEPA ceiling, support columns and seamless flooring ready for equipment installation

Welcome to our Knowledge Hub!

This hub is a practical guide for anyone new to cleanrooms. Whether you are deciding if you need one, choosing a classification, or planning the design, build and ongoing validation, you’ll find plain-English explanations from the engineers at Angstrom Technology, who design, build, validate and maintain cleanrooms across the UK and Europe.

Knowledge hub

The Angstrom Knowledge Hub: expert insights, practical guidance and technical resources on cleanroom design, compliance and operation.

Cleanroom workers

Coming Soon

Keep an eye out for our upcoming Knowledge Hub posts.
Sign Me Up
Cleanroom Acronyms Explained: A Beginners Guide

Cleanroom Acronyms Explained: A Beginners Guide

A practical guide to the most commonly used cleanroom acronyms, helping newcomers navigate industry terminology with confidence.
READ MORE
Ortho5

FFUs vs Centralised HVAC for Cleanrooms

Should your cleanroom use Fan Filter Units (FFUs) or a centralised HVAC system? Compare the pros, cons, costs, flexibility, and ideal applications of each cleanroom…
READ MORE
Large cleanroom reception or material handling area with integrated counters and observation capability for personnel management

Who is responsible for Cleanroom Compliance?

A regulated Cleanroom only stays compliant if everyone knows their role. In practice, responsibility is shared across the organisation and stakeholders.  
READ MORE
5

What do I need to consider when designing a cleanroom?

A Cleanroom project touches far more than just air filters and coverall suits. Missing one key consideration early can lead to expensive changes later.
READ MORE
IMG 6562

How much does a cleanroom cost?

Cleanrooms can vary massively in cost depending on a variety of cost drivers. Typically, the biggest influence is the HVAC system, which must deliver dramatically…
READ MORE
What is the difference between GMP and ISO 14644 Part 1?

What is the difference between GMP and ISO 14644 Part 1?

Understanding the difference between GMP and ISO 14644 is essential for achieving compliance and maintaining cleanroom performance.
READ MORE
shutterstock 24232033 copy

The running cost of a cleanroom & energy conservation

Cleanrooms are notorious for being massively energy consumptive – often using far more power than a standard manufacturing facility of the same size.
READ MORE
Do I need a Cleanroom?

Do I need a cleanroom?

If you’re researching Cleanrooms for the first time, you probably want a clear answer to one simple question: What problem do I have that installing…
READ MORE
CMM suite

How do I know what ISO class my cleanroom should be?

A practical framework for choosing the right ISO 14644 cleanroom class, balancing product risk, cost, and customer requirements.
READ MORE
Do I need a Cleanroom?

What is ISO 14644?

If you’re involved in any validated Cleanroom project, the term “ISO 14644” will most likely appear constantly in the documentation. But what exactly is it,…
READ MORE
Glossary of cleanroom terms

Glossary of cleanroom terms

Explore our glossary to understand essential cleanroom terms and abbreviations.
READ MORE
what is a cleanroom

What is a Cleanroom?

Learn the official cleanroom definition and other cleanroom facts.
READ MORE